publications-equipe-1-en

Team leaders:

B. CHARPENTIER

I. MOTORINE

TEAM 1

RNA-RNP Structure Fonction Maturation

2022

  • SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA. Maharana S, Kretschmer S, Hunger S, Yan X, Kuster D, Traikov S, Zillinger T, Gentzel M, Elangovan S, Dasgupta P, Chappidi N, Lucas N, Maser KI, Maatz H, Rapp A, Marchand V, Chang YT, Motorin Y, Hubner N, Hartmann G, Hyman AA, Alberti S, Lee-Kirsch MA. SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA. Mol Cell. 2022 Oct 6;82(19):3712-3728.e10. doi: 10.1016/j.molcel.2022.08.031. Epub 2022 Sep 22. PMID: 36150385
  • Henry BA, Marchand V, Schlegel BT, Helm M, Motorin Y, Lee N. Pseudouridylation of Epstein-Barr virus noncoding RNA EBER2 facilitates lytic replication. RNA. 2022 Nov;28(11):1542-1552. doi: 10.1261/rna.079219.122. Epub 2022 Sep 13. PMID: 36100352
  •  Hertler J, Slama K, Schober B, Özrendeci Z, Marchand V, Motorin Y, Helm M. Synthesis of point-modified mRNA. Nucleic Acids Res. 2022 Sep 5:gkac719. doi: 10.1093/nar/gkac719. Online ahead of print. PMID: 36062567
  • Chagot ME, Boutilliat A, Kriznik A, Quinternet M. Structural Analysis of the Plasmodial Proteins ZNHIT3 and NUFIP1 Provides Insights into the Selectivity of a Conserved Interaction. Biochemistry. 2022 Apr 5;61(7):479-493. doi: 10.1021/acs.biochem.1c00792. Epub 2022 Mar 22. PMID: 35315277
  • Pompella A, Corti A, Visvikis A.  Redox Mechanisms in Cisplatin Resistance of Cancer Cells: The Twofold Role of Gamma-Glutamyltransferase 1 (GGT1). Front Oncol. 2022 May 20;12:920316. doi: 10.3389/fonc.2022.920316. eCollection 2022. PMID: 35669424 
  • Abel Y, Charron C, Virciglio C, Bourguignon-Igel V, Quinternet M, Chagot ME, Robert MC, Verheggen C, Branlant C, Bertrand E, Manival X, Charpentier B, Rederstorff M. The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity. Nucleic Acids Res. 2022 Feb 28;50(4):2172-2189. doi: 10.1093/nar/gkac086. PMID: 35150569 
  • dos Santos Morais R, Santo P, Ley M, Schelcher C, Abel Y, Plassart L, Deslignière E, Chagot ME, Quinternet M, Paiva A,  Hessmann S, Morellet N,  Sousa P,Vandermoere F, Bertrand E, Charpentier B, Bandeiras T, Plisson-Chastang C, Verheggen C, Cianférani S, Manival X. Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases. J Mol Biol. 2022 Jul 25;434(19):167760. doi: 10.1016/j.jmb.2022.167760. Online ahead of print. PMID: 35901867
  • Dreggors-Walker RE, Cohen LN, Khoshnevis S, Marchand V, Motorin Y, Ghalei H. Studies of mutations of assembly factor Hit 1 in budding yeast suggest translation defects as the molecular basis for PEHO syndrome.  J Biol Chem. 2022 Jul 14:102261. doi: 10.1016/j.jbc.2022.102261. Online ahead of print. PMID: 35843310
  • Pichot F, Marchand V, Helm M, Motorin Y. Machine learning algorithm for precise prediction of 2′-O-methylation (Nm) sites from experimental RiboMethSeq datasets. Methods. 2022 Mar 18:S1046-2023(22)00074-3. doi: 10.1016/j.ymeth.2022.03.007. Online ahead of print. PMID: 35314341
  • Delhermite J, Tafforeau L, Sharma S, Marchand V, Wacheul L, Lattuca R, Desiderio S, Motorin Y, Bellefroid E, Lafontaine DLJ. Systematic mapping of rRNA 2′-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis.  PLoS Genet. 2022 Jan 18;18(1):e1010012. doi: 10.1371/journal.pgen.1010012. eCollection 2022 Jan. PMID: 35041640 Free PMC article.

  • Khoshnevis S, Dreggors-Walker RE, Marchand V, Motorin Y, Ghalei H. Ribosomal RNA 2′-O-methylations regulate translation by impacting ribosome dynamics. Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2117334119. doi: 10.1073/pnas.2117334119. Epub 2022 Mar 16. PMID: 35294285 Free PMC article.

  • Magnus Bäck, Constance Xhaard, Raphael Rouget, Quentin Thuillier, Oscar Plunde, Susanna C Larsson, Nicolas Girerd, João Pedro Ferreira, Jean-Marc Boivin, Erwan Bozec, Ludovic Mercklé, Faiez Zannad, Axelle Hoge, Michèle Guillaume, Claire Dandine-Roulland, Edith Le Floch, Delphine Bacq-Daian, Jean-François Deleuze, Laurie Van den Berghe, Julie-Anne Nazare, Martine Laville, Christiane Branlant, Isabelle Behm-Ansmant, Sandra Wagner, Patrick Rossignol. Fatty acid desaturase genetic variations and dietary omega-3 fatty acid intake associate with arterial stiffness. European Heart Journal Open, oeac016, 2022 March 16, https://doi.org/10.1093/ehjopen/oeac016

Reviews

  • Brégeon D, Pecqueur L, Toubdji S, Sudol C, Lombard M, Fontecave M, de Crécy-Lagard V, Motorin Y, Helm M, Hamdane D.Dihydrouridine in the Transcriptome: New Life for This Ancient RNA Chemical Modification.  ACS Chem Biol. 2022 Jul 15;17(7):1638-1657. doi: 10.1021/acschembio.2c00307. Epub 2022 Jun 23. PMID: 35737906 Review.
  • Motorin Y, Helm M.  RNA nucleotide methylation: 2021 update. Wiley Interdiscip Rev RNA. 2022 Jan;13(1):e1691. doi: 10.1002/wrna.1691. Epub 2021 Dec 15. PMID: 34913259 Review.
  • Helm M, Motorin Y.Phosphorylation found inside RNA.  Nature. 2022 May;605(7909):234-235. doi: 10.1038/d41586-022-01021-6. PMID: 35478019 No abstract available. News&Views

 

2021

  • Schöller E, Marks J, Marchand V, Bruckmann A, Powell CA, Reichold M, Mutti CD, Dettmer K, Feederle R, Hüttelmaier S, Helm M, Oefner P, Minczuk M, Motorin Y, Hafner M, Meister G. Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs. Mol Cell. 2021 Dec 2;81(23):4810-4825.e12. doi: 10.1016/j.molcel.2021.10.018. Epub 2021 Nov 12. PMID: 34774131
  • Baldini L, Robert A, Charpentier B, Labialle S. Phylogenetic and molecular analyses identify SNORD116 targets involved in the Prader Willi syndrome. Mol Biol Evol. 2021 Dec 6:msab348. doi: 10.1093/molbev/msab348.PMID: 34893870
  • Xhaard C, Rouget R, Vodovar N, Le Floch E, Dandine-Roulland C, Wagner S, Bacq-Daian D, Thuillier Q, Boivin JM, Branlant C, Deleuze JF,  Behm-Ansmant I, Zannad F, Rossignol P, Girerd N. Impact of natriuretic peptide polymorphisms on diastolic and metabolic function in a populational cohort: insights from the STANISLAS cohort. ESC Heart Fail. 2021 Nov 3. doi: 10.1002/ehf2.13674
    PMID: 34734498
  • Marchand V, Bourguignon-Igel V, Helm M, Motorin Y. Analysis of pseudouridines and other RNA modifications using HydraPsiSeq protocol.Methods. 2021 Sep 1:S1046-2023(21)00206-1. doi: 10.1016/j.ymeth.2021.08.008. Online ahead of print.PMID: 34481083
  • Motorin Y, Quinternet M, Rhalloussi W, Marchand V. Constitutive and variable 2′-O-methylation (Nm) in human ribosomal RNA. RNA Biol. 2021 Sep 10:1-10. doi: 10.1080/15476286.2021.1974750. Online ahead of print.PMID: 34503375
  • Marchand V, Bourguignon-Igel V, Helm M, Motorin Y. Mapping of 7-methylguanosine (m7G), 3-methylcytidine (m3C), dihydrouridine (D) and 5-hydroxycytidine (ho5C) RNA modifications by AlkAniline-Seq. Methods Enzymol. 2021;658:25-47. doi: 10.1016/bs.mie.2021.06.001. Epub 2021 Jul 12.PMID: 34517949
  • Barthel H, Darne C, Gaté L, Visvikis A, Seidel C. Continuous Long-Term Exposure to Low Concentrations of MWCNTs Induces an Epithelial-Mesenchymal Transition in BEAS-2B Cells. Nanomaterials (Basel). 2021 Jul 1;11(7):1742. doi: 10.3390/nano11071742. PMID: 34361127
  • Alfeghaly C, Sanchez A, Rouget R, Thuillier Q, Igel-Bourguignon V, Marchand V, Branlant C, Motorin Y, Behm-Ansmant I, Maenner S. Implication of repeat insertion domains in the trans-activity of the long non-coding RNA ANRIL. Nucleic Acids Res. 2021 Apr 19 PMID: 33872355
  • Dermouche S, Chagot ME, Manival X, Quinternet M. Optimizing the First TPR Domain of the Human SPAG1 Protein Provides Insight into the HSP70 and HSP90 Binding Properties. Biochemistry. 2021 Mar 19. doi: 10.1021/acs.biochem.1c00052. PMID: 33739091.

  • Bragantini B, Charron C, Bourguet M, Paul A, Tiotiu D, Rothé B, Marty H, Terral G, Hessmann S, Decourty L, Chagot ME, Strub JM, Massenet S, Bertrand E, Quinternet M, Saveanu C, Cianférani S, Labialle S, Manival X, Charpentier B. The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106and controls its transcription dependent activity. Nat Commun. 2021 Mar doi: 10.1038/s41467-021-22077-4. PMID: 33767140
  • Relier S, Ripoll J, Guillorit H, Amalric A, Achour C, Boissière F, VialaretJ, Attina A, Debart F, Choquet A, Macari F, Marchand V, Motorin Y, Samalin E, Vasseur JJ, Pannequin J, Aguilo F, Lopez-Crapez E, Hirtz C, Rivals E, Bastide A, David A. FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell. Nat Commun. 2021 Mar19 doi: 10.1038/s41467-021-21758-4. PMID: 33741917
  • Azevedo-Favory J, Gaspin C, Ayadi L, Montacié C, Marchand V, Jobet E, RompaisM, Carapito C, Motorin Y, Sáez-Vásquez J. Mapping rRNA 2′-O-methylations and identification of C/D snoRNAs in Arabidopsis thaliana plants. RNA Biol. 2021 Feb doi: 10.1080/15476286.2020.1869892.  PMID:33596769.
  • Heiss M, Hagelskamp F, Marchand V, Motorin Y, Kellner S. Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo. Nat Commun. 2021 Jan  doi: 10.1038/s41467-020-20576-4. PMID: 33452242
  • Werner S, Galliot A, Pichot F, Kemmer T, Marchand V, Sednev MV, Lence T, Roignant JY, König J, Höbartner C, Motorin Y, Hildebrandt A, Helm M. NOseq:amplicon sequencing evaluation method for RNA m6A sites after chemical deamination. Nucleic Acids Res. 2021 Feb  doi:10.1093/nar/gkaa1173. PMID: 33313868; PMCID: PMC7913672.
  • Pichot F, Marchand V, Helm M, Motorin Y. Non-Redundant tRNA Reference Sequences for Deep Sequencing Analysis of tRNA Abundance and Epitranscriptomic RNA Modifications. Genes (Basel). 2021 Jan doi:10.3390/genes12010081. PMID: 33435213
  • Abel Y, Paiva ACF, Bizarro J, Chagot ME, Santo PE, Robert MC, Quinternet M, Vandermoere F, Sousa PMF, Fort P, Charpentier B, Manival X, Bandeiras TM, Bertrand E, Verheggen C. NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis. Nucleic Acids Res. 2021 Jan doi: 10.1093/nar/gkaa1226. PMID: 33367824

Methodology chapters

  • Baldini L, Labialle S. Using Native RIP, UV-CLIP or fCLIP to Address Protein-RNA Interactions In Vivo. Methods Mol Biol. 2021;2300:89-98. doi: 10.1007/978-1-0716-1386-3_9.PMID: 33792874
  • Sanchez A, Maenner S. Purification of RiboNucleoProtein Particles by MS2-MBP Affinity Chromatography. Methods Mol Biol. 2021;2300:99-106. doi: 10.1007/978-1-0716-1386-3_10. PMID: 33792875
  • Marchand V, Ayadi L, Bourguignon-Igel V, Helm M, Motorin Y. AlkAniline-Seq: A Highly Sensitive and Specific Method for Simultaneous Mapping of 7-Methyl-guanosine (m7G) and 3-Methyl-cytosine (m3C) in RNAs by High-Throughput Sequencing. Methods Mol Biol. 2021;2298:77-95. doi: 10.1007/978-1-0716-1374-0_5.PMID: 34085239
  • Abel Y, Rederstorff M. Gene Reporter Assays to Study miRNA Function. Methods Mol Biol. 2021;2300:119-131. doi: 10.1007/978-1-0716-1386-3_12. PMID: 33792877.
  • Abel Y, Rederstorff M. Stem-Loop qRT-PCR-Based Quantification of miRNAs. Methods Mol Biol. 2021;2300:59-64. doi: 10.1007/978-1-0716-1386-3_6. PMID:33792871.
  • Bourguignon-Igel V, Abel Y, Rederstorff M. RNA Precipitation. Methods Mol Biol. 2021;2300:11-16. doi: 10.1007/978-1-0716-1386-3_2. PMID: 33792867.
  • Virciglio C, Abel Y, Rederstorff M. Regulatory Non-Coding RNAs: An Overview. Methods Mol Biol. 2021;2300:3-9. doi: 10.1007/978-1-0716-1386-3_1. PMID:33792866.
  • Thuillier Q, Behm-Ansmant I. Microarray Analysis of Whole-Transcriptome RNAs Including Non-Coding RNAs. Methods Mol Biol. 2021;2300:143-164. doi:10.1007/978-1-0716-1386-3_14. PMID: 33792879.
  • Alfeghaly C, Behm-Ansmant I, Maenner S. Study of Genome-Wide Occupancy of Long Non-Coding RNAs Using Chromatin Isolation by RNA Purification (ChIRP). Methods Mol Biol. 2021;2300:107-117. doi: 10.1007/978-1-0716-1386-3_11. PMID:33792876.
  • Vautrot V, Heckler G, Aigueperse C, Behm-Ansmant I. Fluorescence In Situ Hybridization of Small Non-Coding RNAs. Methods Mol Biol. 2021;2300:73-85. doi:10.1007/978-1-0716-1386-3_8. PMID: 33792873.
  • Alfeghaly C, Aigueperse C, Maenner S, Behm-Ansmant I. Non-Coding RNA Silencing in Mammalian Cells by Antisense LNA GapmeRs Transfection. Methods Mol Biol. 2021;2300:31-37. doi: 10.1007/978-1-0716-1386-3_4. PMID: 33792869.
  • Marchand V, Galvanin A, Motorin Y. Isolation, Extraction and Deep-Sequencing Analysis of Extracellular RNAs (exRNAs) from Human Plasma. Methods Mol Biol.2021;2300:165-182. doi: 10.1007/978-1-0716-1386-3_15. PMID: 33792880.
  • Marchand V, Ayadi L, Bourguignon-Igel V, Motorin Y. Quantitative and Qualitative Assessment of Small RNA Preparations. Methods Mol Biol.2021;2300:17-29. doi: 10.1007/978-1-0716-1386-3_3. PMID: 33792868
  • Chagot ME, Quinternet M, Manival X, Lebars I. Application of NMR Spectroscopy to Determine the 3D Structure of Small Non-Coding RNAs. Methods Mol Biol. 2021;2300:251-266. doi: 10.1007/978-1-0716-1386-3_19. PMID: 33792884

Reviews

  • Helm M, Schmidt-Dengler MC, Weber M, Motorin Y. General Principles for the Detection of Modified Nucleotides in RNA by Specific Reagents.  Adv Biol (Weinh). 2021 Oct;5(10):e2100866. doi: 10.1002/adbi.202100866. Epub 2021 Sep 17. PMID: 34535986 Review.
  • Baldini L, Charpentier B, Labialle S. Emerging Data on the Diversity of Molecular Mechanisms Involving C/D snoRNAs.  Noncoding RNA. 2021 May 6;7(2):30. doi: 10.3390/ncrna7020030. PMID: 34066559
  • Marchand V, Motorin Y. Detection and functions of viral RNA modifications: perspectives in biology and medicine. Virologie (Montrouge). 2021 Apr 1;25(2):5-20. doi: 10.1684/vir.2021.0884.PMID: 33973850 
  • Motorin Y, Marchand V. Analysis of RNA Modifications by Second- and Third-Generation Deep Sequencing: 2020 Update. Genes (Basel). 2021 Feb doi: 10.3390/genes12020278. PMID: 33669207.
  • Yoluç Y, Ammann G, Barraud P, Jora M, Limbach PA, Motorin Y, Marchand V, Tisné C, Borland K, Kellner S. Instrumental analysis of RNA modifications. CritRev Biochem Mol Biol. 2021 Apr doi:10.1080/10409238.2021.1887807. PMID: 33618598.

2020 

  •  Marcel V, Kielbassa J, Marchand V, Natchiar KS, Paraqindes H, Nguyen Van Long F, Ayadi L, Bourguignon-Igel V, Lo Monaco P, Monchiet D, Scott V, Tonon L, Bray SE, Diot A, Jordan LB, Thompson AM, Bourdon J-C, Dubois T,  André F,  Catez F, Puisieux A, Motorin Y, Klaholz BP, Viari A, Diaz J-J. (2020). Ribosomal RNA 2′O-methylation as a novel layer of inter-tumour heterogeneity in breast cancer. NAR Cancer, 2(4): pp.zcaa036.

  • Marchand V, Pichot F, Neybecker P, Ayadi LBourguignon-Igel V, Wacheul L, Lafontaine DLJ, Pinzano A, Helm M, Motorin Y. HydraPsiSeq : a method for systematic and quantitative mapping of pseudouridines in RNA. Nucleic Acids Res. 2020 Sep 25:gkaa769. doi : 10.1093/nar/gkaa769. PMID : 32976574
  • ABEL, Y.; PAIVA, A.C.F.; BIZARRO, J.; CHAGOT, M.-E.; SANTO, P.E.; ROBERT, M.-C.; QUINTERNET, M.; VANDERMOERE, F.; SOUSA, P.M.F.; FORT, P.; CHARPENTIER, B.; MANIVAL, X.; BANDEIRAS, T.M.; BERTRAND, E. and VERHEGGEN, C. (2020). NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis. Nucleic Acids Res. 49(2):1094-1113. PMID: 33367824
  •  GALVANIN, A.; VOGT, L.M.; GROBER, A.; FREUND, I.; AYADI, L.; BOURGUIGNON-IGEL, V.; BESSLER, L.; JACOB, D.; EIGENBROD, T., MARCHAND, V.; DALPKE, A.; HELM, M. and MOTORIN, Y. (2020). Bacterial tRNA 2’-O-methylation is dynamically regulated under stress conditions and modulates innate immune response. Nucleic Acids Res. 2020 Dec 4:gkaa1123. doi : 10.1093/nar/gkaa1123. PMID: 33275131
  • Kristen M, Plehn J, Marchand V, Friedland K, Motorin Y, Helm M, Werner S. Manganese Ions Individually Alter the Reverse Transcription Signature of Modified Ribonucleosides. Genes (Basel). 2020 Aug 18 ;11(8):E950. doi : 10.3390/genes11080950. PMID : 32824672 
  • Heckler G, Aigueperse C, Hettal L, Thuillier Q, de Chaumont F, Dallongeville S, Behm-Ansmant I. Substructure Analyzer : A User-Friendly Workflow for Rapid Exploration and Accurate Analysis of Cellular Bodies in Fluorescence Microscopy Images.  J Vis Exp. 2020 Jul 15 ;(161). doi : 10.3791/60990. PMID : 32744525
  • de Crécy-Lagard V, Ross RL, Jaroch M,Marchand V, Eisenhart C, Brégeon D, Motorin Y, Limbach PA. Survey and Validation of tRNA Modifications and Their Corresponding Genes in Bacillus subtilis sp Subtilis Strain 168. Biomolecules. 2020 Jun 30 ;10(7):E977. doi : 10.3390/biom10070977. PMID : 32629984
  • Trzaska C, Amand S, Bailly C, Leroy C, Marchand V, Duvernois-Berthet E, Saliou JM, Benhabiles H, Werkmeister E, Chassat T, Guilbert R, Hannebique D, Mouray A, Copin MC, Moreau PA, Adriaenssens E, Kulozik A, Westhof E, Tulasne D, Motorin Y, Rebuffat S, Lejeune F. 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations. Nat Commun. 2020 Mar 20 ;11(1):1509. doi : 10.1038/s41467-020-15140-z. PMID : 32198346 
  • Pichot F, Marchand V, Ayadi L, Bourguignon-Igel V, Helm M, Motorin Y. Holistic Optimization of Bioinformatic Analysis Pipeline for Detection and Quantification of 2’-O-Methylations in RNA by RiboMethSeq. Front Genet2020 Feb 13 ;11:38. doi : 10.3389/fgene.2020.00038. PMID : 32117451
  • Werner S, Schmidt L, Marchand V, Kemmer T, Falschlunger C, Sednev MV, Bec G, Ennifar E, Höbartner C, Micura R, Motorin Y, Hildebrandt A, Helm M. Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes. Nucleic Acids Res. 2020 Feb 25. pii : gkaa113. doi : 10.1093/nar/gkaa113. PMID : 32095818
  • Chagot ME, Quinternet M, Jacquemin C, Manival X, Gardiennet C. Box C/D snoRNPs : solid-state NMR fingerprint of an early-stage 50 kDa assembly intermediate. Biomol NMR Assign. 2020 Feb 6. doi : 10.1007/s12104-020-09933-y. PMID : 32030621
  • Clerget G, Bourguignon-Igel V, Marmier-Gourrier N, Rolland N, Wacheul L, Manival X, Charron C, Kufel J, Méreau A, Senty-Ségault V, Tollervey D, Lafontaine DLJ, Branlant C, Rederstorff M. Synergistic defects in pre-rRNA processing from mutations in the U3-specific protein Rrp9 and U3 snoRNA. Nucleic Acids Res. 2020 Apr 17 ;48(7):3848-3868. doi : 10.1093/nar/gkaa066. PMID : 31996908
  • Angelova MT, Dimitrova DG, Da Silva B, Marchand V, Jacquier C, Achour C, Brazane M, Goyenvalle C, Bourguignon-Igel V, Shehzada S, Khouider S, Lence T, Guerineau V, Roignant JY, Antoniewski C, Teysset L, Bregeon D, Motorin Y, Schaefer MR, Carré C. tRNA 2’-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in DrosophilaNucleic Acids Res. 2020 Jan 16. pii : gkaa002. doi : 10.1093/nar/gkaa002. PMID : 31943105
clinical publications
  • HETTAL, L., STEFANI, A., SALLERON, J., COURRECH, F., BEHM-ANSMANT, I., CONSTANS, JM., GAUCHOTTE, G. and VOGIN, G. (2020). Radiomics Method for the Differential Diagnosis of Radionecrosis Versus Progression after Fractionated Stereotactic Body Radiotherapy for Brain Oligometastasis. Radiat Res. 193(5):471-480. PMID: 32160109

  • YAKAVETS I, FRANCOIS A, BENOIT A, MERLIN JL, BEZDETNAYA L, VOGIN G (2020). Advanced co-culture 3D breast cancer model for investigation of fibrosis induced by external stimuli: optimization study. Sci Rep. 2020 Dec 4;10(1):21273. doi: 10.1038/s41598-020-78087-7.PMID: 33277538
  • OBARA T, BLONSKI M, BRZENCZEK C, MÉZIÈRES S, GAUDEAU Y, POUGET C, … VOGIN G & al (2020). Adult Diffuse Low-Grade Gliomas: 35-Year Experience at the Nancy France Neurooncology Unit. Front Oncol. 2020 Oct 28;10:574679. doi: 10.3389/fonc.2020.574679. eCollection 2020. PMID: 33194684
  • VOGIN, G ; FAUVEL, M ; HOSSU, G ; BEAUMONT, M ; MICARD, E ; FELTGEN, K & al (2020), Assessing the neuroanatomy knowledge and spatial ability of radiotherapy technologist undergraduates using an interactive volumetric simulation tool-the RadioLOG project., Eur Radiol, 2020, Oct 10. doi: 10.1007/s00330-020-07351-1; PMID: 33037914

Review

  • Rederstorff M. [Decoupling of pre-ribosomal RNA early cleavages by a point mutation in the U3 snoRNA-specific protein Rrp9] Med Sci (Paris). 2020 Apr ;36(4):329-331. Article in French
    PMID : 32356707 

Methodological chapters

  • Vautrot V, Behm-Ansmant I. Enhanced Probe-Based RT-qPCR Quantification of MicroRNAs Using Poly(A) Tailing and 5’ Adaptor Ligation. Methods Mol Biol. 2020 ;2065:39-54.  PMID : 31578686

2019

  • ACL-28 Khoury G, Mackenzie C, Ayadi L, Lewin SR, Branlant C, Purcell DFJ. Tat IRES modulator of tat mRNA (TIM-TAM) : a conserved RNA structure that controls Tat expression and acts as a switch for HIV productive and latent infection. Nucleic Acids Res. 2019 Dec 25. pii : gkz1181. doi : 10.1093/nar/gkz1181. 2019 Q1, IF 11.501
    PMID : 31875221 
  • REV-10 Helm M, Lyko F, Motorin Y. Limited antibody specificity compromises epitranscriptomic analyses. Nat Commun. 2019 Dec 11 ;10(1):5669. doi : 10.1038/s41467-019-13684-3. Comment. 2019 Q1, IF 12.121
    PMID : 31827101 
  • ACL-27 Schmidt L, Werner S, Kemmer T, Niebler S, Kristen M, Ayadi L, Johe P, Marchand V, Schirmeister T, Motorin Y, Hildebrandt A, Schmidt B, Helm M. Graphical Workflow System for Modification Calling by Machine Learning of Reverse Transcription Signatures. Front Genet. 2019 Sep 25 ;10:876. doi : 10.3389/fgene.2019.00876. 2019 Q2, IF 3.258
    PMID : 31608115 
  • ACL-25 Chagot ME, Dos Santos Morais R, Dermouche S, Lefebvre D, Manival X, Chipot C, Dehez F, Quinternet M. Binding properties of the quaternary assembly protein SPAG1. Biochem J. 2019 Jun 14 ;476(11):1679-1694. doi : 10.1042/BCJ20190198. 2019 Q2, IF 4.097
    PMID : 31118266
  • REV-8 Motorin Y, Massenet S. RNA structure, maturation, interactions and functions. Editorial introduction forthe Special issue dedicated to 2019 SIFRARN meeting in Nancy. Biochimie. 2019 Jul 17. pii : S0300-9084(19)30204-4. doi:10.1016/j.biochi.2019.07.013. Review. 2019 Q2, IF 3.413
    PMID : 31325478
  • REV-6 Abel Y, Rederstorff M. SnoRNAs and the emerging class of sdRNAs : Multifaceted players in oncogenesis. Biochimie. 2019 May 9. pii : S0300-9084(19)30145-2. doi : 10.1016/j.biochi.2019.05.006. Review. 22019 Q2, IF 3.413
    PMID : 31078583
  • ACL-21 Galvanin A, Dostert G, Ayadi L, Marchand V, Velot É, Motorin Y. Diversity and heterogeneity of extracellular RNA in human plasma. Biochimie. 2019 May 17. pii : S0300-9084(19)30150-6. doi : 10.1016/j.biochi.2019.05.011. 2019 Q2, IF 3.413
    PMID : 31108123
  • ACL-20 Freund I, Buhl DK, Boutin S, Kotter A, Pichot F, Marchand V, Vierbuchen T, Heine H, Motorin Y, Helm M, Dalpke AH, Eigenbrod T. 2’-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms. RNA. 2019 Apr 24. pii : rna.070243.118. doi : 10.1261/rna.070243.118. 2019 Q2, IF 4.320
    PMID : 31019095
  • REV-7 Massenet S. In vivo assembly of eukaryotic signal recognition particle : A still enigmatic process involving the SMN complex. Biochimie. 2019 Apr 9. pii : S0300-9084(19)30109-9. doi : 10.1016/j.biochi.2019.04.007. Review. 2019 Q2, IF 3.413
    PMID : 30978374
  • ACL-19 Chagot ME, Quinternet M, Rothé B, Charpentier B, Coutant J, Manival X, Lebars I. The yeast C/D box snoRNA U14 adopts a “weak” K-turn like conformation recognized by the Snu13 core protein in solution. Biochimie. 2019 Mar 23. pii : S0300-9084(19)30083-5. doi : 10.1016/j.biochi.2019. 03.014.2019 Q2, IF 3.413
    PMID : 30914254
  • ACL-23 Paul A, Tiotiu D, Bragantini B, Marty H, Charpentier B, Massenet S, Labialle S. Bcd1p controls RNA loading of the core protein Nop58 during C/D box snoRNP biogenesis. RNA. 2019 Apr ;25(4):496-506. doi : 10.1261/rna.067967.118. 2019 Q2, IF 4.320
    PMID : 30700579
  • ACL-22 Jacob D, Thüring K, Galliot A, Marchand V, Galvanin A, Ciftci A, Scharmann K, Stock M, Roignant JY, Leidel SA, Motorin Y, Schaffrath R, Klassen R, Helm M. Absolute quantification of noncoding RNA by microscale thermophoresis.Angew Chem Int Ed Engl. 2019 Mar 20. doi : 10.1002/anie.201814377. 2019 Q1, IF 12.959
    PMID : 30892798.
  • ACL-26 Wei J, Kishton RJ, Angel M, Conn CS, Dalla-Venezia N, Marcel V, Vincent A, Catez F, Ferré S, Ayadi L, Marchand V, Dersh D, Gibbs JS, Ivanov IP, Fridlyand N, Couté Y, Diaz JJ, Qian SB, Staudt LM, Restifo NP, Yewdell JW. Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance. Mol Cell. 2019 Jan 24. pii : S1097-2765(18)31096-7. doi : 10.1016/j.molcel.2018.12.020. 2019 Q1, IF 15.584
    PMID : 30712990.
  • REV-9 Motorin Y, Helm M. Methods for RNA Modification Mapping Using Deep Sequencing : Established and New Emerging Technologies. Genes (Basel). 2019 Jan 9 ;10(1). pii : E35. doi : 10.3390/genes10010035. Review. 2019 Q2, IF 3.759
    PMID : 30634534.
  • ACL-24 Ringeard M, Marchand V, Decroly E, Motorin Y, Bennasser Y. FTSJ3 is an RNA 2’-O-methyltransferase recruited by HIV to avoid innate immune sensing. Nature. 2019 Jan 9. doi : 10.1038/s41586-018-0841-4. 2019 Q1, IF 42.778
    PMID:30626973.
  • CHAP-3 Galvanin A, Ayadi L, Helm M, Motorin Y, Marchand V. Mapping and Quantification of tRNA 2’-O-Methylation by RiboMethSeq. Methods Mol Biol. 2019 ;1870:273-295. doi : 10.1007/978-1-4939-8808-2_21.
    PMID : 30539563

2018

  • REV-5 Ayadi L, Galvanin A, Pichot F, Marchand V, Motorin Y. RNA ribose methylation (2’-O-methylation) : Occurrence, biosynthesis and biological functions. Biochim Biophys Acta Gene Regul Mech. 2018 Dec 17. pii : S1874-9399(18)30080-4. doi : 10.1016/j.bbagrm.2018.11.009. Review. 2018 Q1, IF 4.599
    PMID : 30572123
  • REV-4 Motorin Y, Marchand V. Detection and Analysis of RNA Ribose 2’-O-Methylations : Challenges and Solutions. Genes (Basel). 2018 Dec 18 ;9(12). pii : E642. doi : 10.3390/genes9120642. Review. 2018 Q2, IF 3.331
    PMID : 30567409
  • ACL-16 Marchand V, Ayadi L, Ernst FGM, Hertler J, Bourguignon-Igel V, Galvanin A, Kotter A, Helm M, Lafontaine DLJ, Motorin Y. AlkAniline-Seq : profiling of m7G and m3C RNA modifications at single nucleotide resolution. Angew Chem Int Ed Engl. 2018 Oct 29. doi : 10.1002/anie.201810946. 2018 Q1, IF 12.257
    PMID : 30370969
  • ACL-12 Fujikane R, Behm-Ansmant I, Tillault AS, Loegler C, Igel-Bourguignon V, Marguet E, Forterre P, Branlant C, Motorin Y, Charpentier B. Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA :Ψ-synthase activities of the archaeal Cbf5 protein.Sci Rep. 2018 Sep 14 ;8(1):13815. doi : 10.1038/s41598-018-32164-0. 2018 Q1, IF 4.011
    PMID:30218085
  • ACL-15 Keller P, Freund I, Marchand V, Bec G, Huang R, Motorin Y, Eigenbrod T, Dalpke A, Helm M. Double methylation of tRNA-U54 to 2’-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7. Nucleic Acids Res. 2018 Aug 8. doi : 10.1093/nar/gky644. 2018 Q1, IF 11.147
    PMID:30102387
  • ACL-14 Henri J, Chagot ME, Bourguet M, Abel Y, Terral G, Maurizy C, Aigueperse C, Georgescauld F, Vandermoere F, Saint-Fort R, Behm-Ansmant I, Charpentier B, Pradet-Balade B, Verheggen C, Bertrand E, Meyer P, Cianférani S, Manival X, Quinternet M. Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. Structure. 2018 Jul 18. pii : S0969-2126(18)30208-9. doi : 10.1016/j.str.2018.06.002. 2018 Q1, IF 4.576
    PMID:30033218
  • REV-3 Jantsch MF, Quattrone A, O’Connell M, Helm M, Frye M, Macias-Gonzales M, Ohman M, Ameres S, Willems L, Fuks F, Oulas A, Vanacova S, Nielsen H, Bousquet-Antonelli C, Motorin Y, Roignant JY, Balatsos N, Dinnyes A, Baranov P, Kelly V, Lamm A, Rechavi G, Pelizzola M, Liepins J, Holodnuka Kholodnyuk I, Zammit V, Ayers D, Drablos F, Dahl JA, Bujnicki J, Jeronimo C, Almeida R, Neagu M, Costache M, Bankovic J, Banovic B, Kyselovic J, Valor LM, Selbert S, Pir P, Demircan T, Cowling V, Schäfer M, Rossmanith W, Lafontaine D, David A, Carre C, Lyko F, Schaffrath R, Schwartz S, Verdel A, Klungland A, Purta E, Timotijevic G, Cardona F, Davalos A, Ballana E, O Carroll D, Ule J, Fray R. Positioning Europe for the EPITRANSCRIPTOMICS challenge. RNA Biol. 2018 May 9:1-3. doi : 10.1080/15476286.2018.1460996. Review. 2018 Q1, IF 5.477
    PMID:29671387
  • ACL-17 Maurizy C, Quinternet M, Abel Y, Verheggen C, Santo PE, Bourguet M, C F Paiva A, Bragantini B, Chagot ME, Robert MC, Abeza C, Fabre P, Fort P, Vandermoere F, M F Sousa P, Rain JC, Charpentier B, Cianférani S, Bandeiras TM, Pradet-Balade B, Manival X, Bertrand E. The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones. Nat Commun. 2018 May 29 ;9(1):2093. doi : 10.1038/s41467-018-04431-1. 2018 Q1, IF 11.878
    PMID:29844425
  • ACL-11 Dal Magro C, Keller P, Kotter A, Werner S, Duarte V, Marchand V, Ignarski M, Freiwald A, Müller RU, Dieterich C, Motorin Y, Butter F, Atta M, Helm M. A vastly increased chemical variety of RNA modifications that includes a thioacetal structure. Angew Chem Int Ed Engl. 2018 Apr 6. doi : 10.1002/anie.201713188. 2018 Q1, IF 12.257
    PMID : 29624844
  • ACL-10 Bragantini B, Rouillon C, Charpentier B, Manival X, Quinternet M. NMR assignment and solution structure of the external DII domain of the yeast Rvb2 protein. Biomol NMR Assign. 2018 Mar 22. doi : 10.1007/s12104-018-9816-5. 2018 Q4, IF 0.576
    PMID : 29569106
  • ACL-18 Weldon C, Dacanay JG, Gokhale V, Boddupally PVL, Behm-Ansmant I, Burley GA, Branlant C, Hurley LH, Dominguez C, Eperon IC. Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X. Nucleic Acids Res. 2018 Jan 25 ;46(2):886-896. doi : 10.1093/nar/gkx1122. 2018 Q1, IF 11.147
    PMID : 29156002
  • CHAP- 2 Ayadi L, Motorin Y, Marchand V. Quantification of 2’-O-Me Residues in RNA Using Next-Generation Sequencing (Illumina RiboMethSeq ProtoACL-14 col). Methods Mol Biol. 2018 ;1649:29-48. doi : 10.1007/978-1-4939-7213-5_2.
    PMID:29130188
  • ACL-13 Guéant JL, Chéry C, Oussalah A, Nadaf J, Coelho D, Josse T, Flayac J, Robert A, Koscinski I, Gastin I, Filhine-Tresarrieu P, Pupavac M, Brebner A, Watkins D, Pastinen T, Montpetit A, Hariri F, Tregouët D, Raby BA, Chung WK, Morange PE, Froese DS, Baumgartner MR, Benoist JF, Ficicioglu C, Marchand V, Motorin Y, Bonnemains C, Feillet F, Majewski J, Rosenblatt DS. A PRDX1 mutant allele causes a MMACHC secondary epimutation in cblC patients. Nat Commun. 2018 Jan 4 ;9(1):67. doi : 10.1038/s41467-017-02306-5. Erratum in : Nat Commun. 2018 Feb 2 ;9(1):554. 2018 Q1, IF 11.878
    PMID : 29302025
  • ACL-9 Aschenbrenner J, Werner S, Marchand V, Adam M, Motorin Y, Helm M, Marx A. Engineering of a DNA Polymerase for Direct m6A Sequencing. Angew Chem Int Ed Engl. 2018 Jan 8 ;57(2):417-421. doi : 10.1002/anie.201710209. 2018 Q1, IF 12.257
    PMID : 29115744

2017

  • ACL-1 Erales J, Marchand V, Panthu B, Gillot S, Belin S, Ghayad SE, Garcia M, Laforêts F, Marcel V, Baudin-Baillieu A, Bertin P, Couté Y, Adrait A, Meyer M, Therizols G, Yusupov M, Namy O, Ohlmann T, Motorin Y, Catez F, Diaz JJ. Evidence for rRNA 2’-O-methylation plasticity : Control of intrinsic translational capabilities of human ribosomes. Proc Natl Acad Sci U S A. 2017 Dec 5 ;114(49):12934-12939. doi : 10.1073/pnas.1707674114. 2017 Q1, IF 9.504
    PMID : 29158377
  • ACL-7 Sharma S, Marchand V, Motorin Y, Lafontaine DLJ. Identification of sites of 2’-O-methylation vulnerability in human ribosomal RNAs by systematic mapping. Sci Rep. 2017 Sep 13 ;7(1):11490. doi : 10.1038/s41598-017-09734-9. 2017 Q1, IF 4.122
    PMID : 28904332
  • ACL-8 Weldon C, Behm-Ansmant I, Hurley LH, Burley GA, Branlant C, Eperon IC, Dominguez C. Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA. Nat Chem Biol. 2017 Jan ;13(1):18-20. doi : 10.1038/nchembio.2228. Epub 2016 Nov 7. 2017 Q1, IF 13.843
    PMID:27820800
  • ACL-5 Moulin D, Salone V, Koufany M, Clément T, Behm-Ansmant I, Branlant C, Charpentier B, Jouzeau JY. MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes. Biomed Res Int. 2017 ;2017:9792512. doi : 10.1155/2017/9792512. 2017 Q3, IF 2.583
    PMID : 28612031
  • REV-1 Helm M, Motorin Y. Detecting RNA modifications in the epitranscriptome : predict and validate. Nat Rev Genet. 2017 May ;18(5):275-291. doi : 10.1038/nrg.2016.169. Review. 2017 Q1, IF 41.465
    PMID:28216634
  • ACL-4 Marchand V, Pichot F, Thüring K, Ayadi L, Freund I, Dalpke A, Helm M, Motorin Y. Next-Generation Sequencing-Based RiboMethSeq Protocol for Analysis of tRNA 2’-O-Methylation. Biomolecules. 2017 Feb 9 ;7(1). pii : E13. doi : 10.3390/biom7010013. 2018 Q1, IF 4.694
    PMID:28208788
  • CHAP-1 Marchand V, Ayadi L, El Hajj A, Blanloeil-Oillo F, Helm M, Motorin Y. High-Throughput Mapping of 2’-O-Me Residues in RNA Using Next-Generation Sequencing (Illumina RiboMethSeq Protocol). Methods Mol Biol. 2017 ;1562:171-187. doi : 10.1007/978-1-4939-6807-7_12.
    PMID:28349461
  • ACL-3 Gribling-Burrer AS, Leichter M, Wurth L, Huttin A, Schlotter F, Troffer-Charlier N, Cura V, Barkats M, Cavarelli J, Massenet S, Allmang C. SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation. Nucleic Acids Res. 2017 Jan 23. pii : gkx031. doi : 10.1093/nar/gkx031. 2017 Q1, IF 11.147
    PMID:28115638
  • REV-2 Schwartz S, Motorin Y. Next-generation sequencing technologies for detection of modified nucleotides in RNAs. RNA Biol. 2017 Sep 2 ;14(9):1124-1137. doi :
    10.1080/15476286.2016.1251543. Review. 2017 Q1, IF 5.067
    PMID : 27791472
  • ACL-6 Rothé B, Manival X, Rolland N, Charron C, Senty-Ségault V, Branlant C, Charpentier B. Implication of the box C/D snoRNP assembly factor Rsa1p in U3 snoRNP assembly. Nucleic Acids Res. 2017 May 13. doi : 10.1093/nar/gkx424. 2017 Q1, IF 11.147
    PMID:28505348

2016

  • Richard M, Chateau A, Jelsch C, Didierjean C, Manival X, Charron C, Maigret B, Barberi-Heyob M, Chapleur Y, Boura C, Pellegrini-Moïse N. Carbohydrate-based peptidomimetics targeting neuropilin-1 : Synthesis, molecular docking study and in vitro biological activities. Bioorg Med Chem. 2016 Nov 1 ;24(21):5315-5325.
    PMID :27622745
  • Quinternet M, Chagot ME, Rothé B, Tiotiu D, Charpentier B, Manival X. Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species. Structure. 2016 Oct 4 ;24(10):1693-1706.
    PMID :27594683
  • Hauenschild R, Werner S, Tserovski L, Hildebrandt A, Motorin Y, Helm M. (2016) CoverageAnalyzer (CAn) : A Tool for Inspection of Modification Signatures in RNA Sequencing Profiles. Biomolecules. 2016 Nov 10 ;6(4). pii : E42. 2018 Q1, IF 4.694
    PMID:27834909
  • Massenet S, Bertrand E, Verheggen C (2016) Assembly and trafficking of box C/D and H/ACA snoRNPs. RNA Biol. 2016 Oct 7:1-13. doi : 10.1080/15476286.2016.1243646. 2016 Q2, IF 3.900
    PMID:27715451
  • Tserovski L, Marchand V, Hauenschild R, Blanloeil-Oillo F, Helm M, Motorin Y. High-throughput sequencing for 1-methyladenosine (m(1)A) mapping in RNA. Methods. 2016 Sep 1 ;107:110-21. doi : 10.1016/j.ymeth.2016.02.012. 2016 Q2, IF 3.802
    PMID : 26922842 

  • BRAGANTINI B.$ ; TIOTIU D.$ ; ROTHE B. ; SALIOU J. M. ; MARTY H. ; CIANFERANI S. ; CHARPENTIER B. ; QUINTERNET M. and MANIVAL X.* (2016). Functional and structural insights of the Zinc-Finger HIT protein family members involved in Box C/D snoRNP biogenesis. Journal of Molecular Biology, 428 : 2488-2506. 2016 Q1, IF 4.632
  • Marchand V, Blanloeil-Oillo F, Helm M, Motorin Y.* (2016). Illumina-based RiboMethSeq approach for mapping of 2’-O-Me residues in RNA. Nucleic Acids Research, 2016 Sep 19 ;44(16):e135. doi : 10.1093/nar/gkw547. 2016 Q1, IF 10.162
  • Motorin Y, Seidu-Larry S, Helm M. (2016). DNA and RNA pyrimidine nucleobase alkylation at the carbon-5 position. DNA Methyltransferases – Role and Function. Ed Prof. Dr. Albert Jeltsch and Dr. Renata Z. Jurkowska, Springer. Adv Exp Med Biol. 2016 ;945:19-33. Review. 2016 Q2, IF 1.937
    PMID : 27826833

2015

  • BIZARRO J. ; DODRE M. ; HUTTIN A. ; CHARPENTIER B. ; SCHLOTTER F. ; BRANLANT C. ; VERHEGGEN C.* ; MASSENET S.* and BERTRAND E.* (2015). NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins. Nucleic Acids Research, 43 : 8973-8989.
  • BOURGEOIS G.$ ; NEY M.$ ; GASPAR I. ; AIGUEPERSE C. ; SCHAEFER M. ; KELLNER S. ; HELM M. and MOTORIN Y.* (2015). Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120. PloS One, 10 : e0133321.
  • HAUENSCHILD R.$ ; TSEROVSKI L.$ ; SCHMID K. ; THURING K. ; WINZ M. L. ; SHARMA S. ; ENTIAN K. D. ; WACHEUL L. ; LAFONTAINE D. L. ; ANDERSON J. ; ALFONZO J. ; HILDEBRANDT A. ; JASCHKE A. ; MOTORIN Y.* and HELM M.* (2015). The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent. Nucleic Acids Research, 43 : 9950-9964.
  • MANIVAL X. ; JACQUEMIN C. ; CHARPENTIER B. and QUINTERNET M.* (2015). (1)H, (15)N and (13)C resonance assignments of the yeast Pih1 and Tah1 C-terminal domains complex. Biomolecular NMR Assignments, 9 : 71-73.
  • QUINTERNET M. ; ROTHE B. ; BARBIER M. ; BOBO C. ; SALIOU J. M. ; JACQUEMIN C. ; BACK R. ; CHAGOT M. E. ; CIANFERANI S. ; MEYER P. ; BRANLANT C. ; CHARPENTIER B. and MANIVAL X.* (2015). Structure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP Assembly. Journal of Molecular Biology, 427 : 2816-2839.
  • SALIOU J. M. ; MANIVAL X. ; TILLAULT A. S. ; ATMANENE C. ; BOBO C. ; BRANLANT C. ; VAN DORSSELAER A. ; CHARPENTIER B. and CIANFERANI S.* (2015). Combining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity. Proteomics, 15 : 2851-2861.
  • CHAGOT M. E. ; JACQUEMIN C. ; BRANLANT C. ; CHARPENTIER B. ; MANIVAL X. and QUINTERNET M.* (2015). (1)H, (15)N and (13)C resonance assignments of the two TPR domains from the human RPAP3 protein. Biomolecular NMR Assignments, 9 : 99-102.
  • TILLAULT A. S.$ ; FOURMANN J. B.$ ; LOEGLER C. ; BLAUD M. ; BRANLANT C. and CHARPENTIER B.* (2015). RNA size is a critical factor for U-containing substrate selectivity and permanent pseudouridylated product release during the RNA:Psi-synthase reaction catalyzed by box H/ACA sRNP enzyme at high temperature. Biochimie, 113 : 134-142.
  • TILLAULT A. S.$ ; FOURMANN J. B.$ ; LOEGLER C. ; WIEDEN H. J. ; KOTHE U. and CHARPENTIER B.* (2015). Contribution of two conserved histidines to the dual activity of archaeal RNA guide-dependent and -independent pseudouridine synthase Cbf5. RNA, 21 : 1233-1239.
  • VAUTROT V. ; AIGUEPERSE C. ; OILLO-BLANLOEIL F. ; HUPONT S. ; STEVENIN J. ; BRANLANT C.* and BEHM-ANSMANT I.* (2015). Enhanced SRSF5 Protein Expression Reinforces Lamin A mRNA Production in HeLa Cells and Fibroblasts of Progeria Patients. Human Mutation, 37 : 280-291.
  • ABEL Y. and REDERSTORFF M. (2015). Gene expression knockdown by transfection of siRNAs into mammalian cells. Methods in Molecular Biology, 1296 : 199-202.
  • CLEMENT T. ; SALONE V. and REDERSTORFF M. (2015). Dual luciferase gene reporter assays to study miRNA function. Methods in Molecular Biology, 1296 : 187-198.
  • CLERGET G. ; ABEL Y. and REDERSTORFF M. (2015). Small non-coding RNAs : a quick look in the rearview mirror. Methods in Molecular Biology, 1296 : 3-9.
  • CLERGET G. ; BOURGUIGNON-IGEL V. and REDERSTORFF M. (2015). Alcoholic precipitation of small non-coding RNAs. Methods in Molecular Biology, 1296 : 11-16.
  • MARCHAND V. and BRANLANT C. (2015). Quantification and quality control of a small non-coding RNA preparation. Methods in Molecular Biology, 1296 : 17-28.
  • MOTORIN Y. (2015) RNA Modification In : Encyclopedia of Life Sciences (eLS). John Wiley& Sons, Ltd : Chichester. DOI : 10.1002/9780470015902.a0000528.pub3.
  • PHILIPPE J. V. ; AYADI L. ; BRANLANT C. and BEHM-ANSMANT I. (2015). Probing small non-coding RNAs structures. Methods in Molecular Biology, 1296 : 119-136.
  • REDERSTORFF M. (EDITOR). (2015). Small non-coding RNA, methods and protocols. Methods in Molecular Biology, 1296.
  • SALONE V. and REDERSTORFF M. (2015). Stem-loop RT-PCR based quantification of small non-coding RNAs. Methods in Molecular Biology, 1296 : 103-108.
  • VAUTROT V. ; AIGUEPERSE C. ; BRANLANT C. and BEHM-ANSMANT I. (2015). Fluorescence in situ hybridization of small non-coding RNAs. Methods in Molecular Biology, 1296 : 73-83.

2014

  • BIZARRO J.$ ; CHARRON C.$ ; BOULON S. ; WESTMAN B. ; PRADET-BALADE B. ; VANDERMOERE F. ; CHAGOT M. E. ; HALLAIS M. ; AHMAD Y. ; LEONHARDT H. ; LAMOND A. ; MANIVAL X. ; BRANLANT C. ; CHARPENTIER B. ; VERHEGGEN C.* and BERTRAND E.* (2014). Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control. The Journal of Cell Biology, 207 : 463-480.
  • CARPENTIER C. ; GHANEM D. ; FERNANDEZ-GOMEZ F. J. ; JUMEAU F. ; PHILIPPE J. V. ; FREYERMUTH F. ; LABUDECK A. ; EDDARKAOUI S. ; DHAENENS C. M. ; HOLT I. ; BEHM-ANSMANT I. ; MARMIER-GOURRIER N. ; BRANLANT C. ; CHARLET-BERGUERAND N. ; MARIE J. ; SCHRAEN-MASCHKE S. ; BUEE L. ; SERGEANT N.* and CAILLET-BOUDIN M. L.* (2014). Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2. Biochimica et Biophysica Acta, 1842 : 654-664. Q1
  • ROTHE B. ; BACK R. ; QUINTERNET M. ; BIZARRO J. ; ROBERT M. C. ; BLAUD M. ; ROMIER C. ; MANIVAL X.* ; CHARPENTIER B.* ; BERTRAND E.* and BRANLANT C. (2014). Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly. Nucleic Acids Research, 42 : 2015-2036.
  • ROTHE B. ; SALIOU J. M. ; QUINTERNET M. ; BACK R. ; TIOTIU D. ; JACQUEMIN C. ; LOEGLER C. ; SCHLOTTER F. ; PENA V. ; ECKERT K. ; MORERA S. ; DORSSELAER A. V. ; BRANLANT C.* ; MASSENET S. ; SANGLIER-CIANFERANI S. ; MANIVAL X. and CHARPENTIER B.* (2014). Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction. Nucleic Acids Research, 42 : 10731-10747.
  • CLEMENT T. ; SALONE V. ; CHARPENTIER B. ; JOUZEAU J. Y. and BIANCHI A. (2014). Identification of new microRNAs targeting genes regulating the Pi/PPi balance in chondrocytes. Bio-medical Materials and Engineering, 24 : 3-16.
  • MOTORIN Y.* and CHARPENTIER B. (2014). RNA Modification. Reviews in cell biology and molecular medicine (Encyclopedia of Molecular Cell Biology and Molecular Medicine), 1-47.
  • SPENKUCH F. ; MOTORIN Y. and HELM M.* (2014). Pseudouridine : still mysterious, but never a fake (uridine) ! RNA Biology, 11 : 1540-1554.
  • MARCHAND V. ; MOUGIN A. ; MEREAU A. ; BEHM-ANSMANT I. ; MOTORIN Y. ; and BRANLANT C. (2014). Study of RNA-Protein Interactions and RNA Structure in Ribonucleoprotein Particles. Handbook of RNA Biochemistry, Second, completely revised and enlarged Edition, Edited by HARTMANN R. K. ; BINDEREIF A. ; SCHON A. ; and WESTHOF E. ; Wiley-VCH Verlag GmbH and Co. KGaA, Volume 2, chapter 44, 975-1015.
  • ABEL Y. ; CLERGET G. ; BOURGUIGNON-IGEL V. ; SALONE V. and REDERSTORFF M.* (2014). Beyond usual functions of snoRNAs. Medecine Sciences : M/S, 30 : 297-302.

2013

  • BACK R. ; DOMINGUEZ C. ; ROTHE B. ; BOBO C. ; BEAUFILS C. ; MORERA S. ; MEYER P. ; CHARPENTIER B. ; BRANLANT C. ; ALLAIN F. H.* and MANIVAL X.* (2013). High-resolution structural analysis shows how Tah1 tethers Hsp90 to the R2TP complex. Structure, 21 : 1834-1847.
  • BOS J. ; DUVERGER Y. ; THOUVENOT B. ; CHIARUTTINI C. ; BRANLANT C. ; SPRINGER M. ; CHARPENTIER B. and BARRAS F.* (2013). The sRNA RyhB regulates the synthesis of the Escherichia coli methionine sulfoxide reductase MsrB but not MsrA. PloS One, 8 : e63647.
  • FOURMANN J. B.$ ; TILLAULT A. S.$ ; BLAUD M.$ ; LECLERC F. ; BRANLANT C. and CHARPENTIER B.* (2013). Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases : relation between conformational dynamics of the guide RNA, enzyme assembly and activity. PloS One, 8 : e70313.
  • PIAZZON N. ; SCHLOTTER F. ; LEFEBVRE S. ; DODRE M. ; MEREAU A. ; SORET J. ; BESSE A. ; BARKATS M. ; BORDONNE R. ; BRANLANT C. and MASSENET S.* (2013). Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle. Nucleic Acids Research, 41 : 1255-1272.
  • BOSCHI-MULLER S. and MOTORIN Y. (2013). Chemistry enters nucleic acids biology : enzymatic mechanisms of RNA modification. Biochemistry (Mosc), 78 : 1392-1404.

2012

  • MARMIER-GOURRIER N. ; VAUTRIN A. ; BRANLANT C. and BEHM-ANSMANT I. (2012). Analyses of site-specific RNA-protein interactions. Edited by STAMM S. ; SMITH C. ; and LUHRMANN R. ; Wiley-Blackwell, chapter 32, 343-355.
  • REDERSTORFF M. (2012). Generation of cDNA libraries from RNP-derived regulatory noncoding RNAs. Methods in Molecular Biology, 925 : 211-218.
  • SKREKA K. and REDERSTORFF M. (2012). [A hybrid microarray for the analysis of a miscellaneous ncRNA population]. Medecine Sciences : M/S, 28 : 819-821.

2011

  • BAR A. ; MARCHAND V. ; KHOURY G. ; DREUMONT N. ; MOUGIN A. ; ROBAS N. ; STEVENIN J. ; VISVIKIS A. and BRANLANT C.* (2011). Structural and functional analysis of the Rous Sarcoma virus negative regulator of splicing and demonstration of its activation by the 9G8 SR protein. Nucleic Acids Research, 39 : 3388-3403.
  • KELLNER S. ; SEIDU-LARRY S. ; BURHENNE J. ; MOTORIN Y. and HELM M.* (2011). A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA. Nucleic Acids Research, 39 : 7348-7360.
  • LOPEZ-MEJIA I. C. ; VAUTROT V. ; DE TOLEDO M. ; BEHM-ANSMANT I. ; BOURGEOIS C. F. ; NAVARRO C. L. ; OSORIO F. G. ; FREIJE J. M. ; STEVENIN J. ; DE SANDRE-GIOVANNOLI A. ; LOPEZ-OTIN C. ; LEVY N. ; BRANLANT C. and TAZI J.* (2011). A conserved splicing mechanism of the LMNA gene controls premature aging. Human Molecular Genetics, 20 : 4540-4555.
  • MARCHAND V.$ ; SANTERRE M.$ ; AIGUEPERSE C. ; FOUILLEN L. ; SALIOU J. M. ; VAN DORSSELAER A. ; SANGLIER-CIANFERANI S. ; BRANLANT C.* and MOTORIN Y. (2011). Identification of protein partners of the human immunodeficiency virus 1 tat/rev exon 3 leads to the discovery of a new HIV-1 splicing regulator, protein hnRNP K. RNA Biology, 8 : 325-342.
  • MARMIER-GOURRIER N.$ ; CLERY A.$ ; SCHLOTTER F. ; SENTY-SEGAULT V. and BRANLANT C.* (2011). A second base pair interaction between U3 small nucleolar RNA and the 5’-ETS region is required for early cleavage of the yeast pre-ribosomal RNA. Nucleic Acids Research, 39 : 9731-9745.
  • MOTORIN Y. ; BURHENNE J. ; TEIMER R. ; KOYNOV K. ; WILLNOW S. ; WEINHOLD E. and HELM M.* (2011). Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling. Nucleic Acids Research, 39 : 1943-1952.
  • TRAN H.$ ; GOURRIER N.$ ; LEMERCIER-NEUILLET C.$ ; DHAENENS C. M. ; VAUTRIN A. ; FERNANDEZ-GOMEZ F. J. ; ARANDEL L. ; CARPENTIER C. ; OBRIOT H. ; EDDARKAOUI S. ; DELATTRE L. ; VAN BRUSSELS E. ; HOLT I. ; MORRIS G. E. ; SABLONNIERE B. ; BUEE L. ; CHARLET-BERGUERAND N. ; SCHRAEN-MASCHKE S. ; FURLING D. ; BEHM-ANSMANT I. ; BRANLANT C. ; CAILLET-BOUDIN M. L. and SERGEANT N.* (2011). Analysis of exonic regions involved in nuclear localization, splicing activity, and dimerization of Muscleblind-like-1 isoforms. The Journal of Biological Chemistry, 286 : 16435-16446.
  • BEHM-ANSMANT I. ; HELM M. and MOTORIN Y.* (2011). Use of specific chemical reagents for detection of modified nucleotides in RNA. Journal of nucleic acids, 2011 : 408053.
  • MOTORIN Y.* and HELM M. (2011). RNA nucleotide methylation. Wiley interdisciplinary reviews. RNA, 2 : 611-631.

2010

  • DREUMONT N. ; HARDY S. ; BEHM-ANSMANT I. ; KISTER L. ; BRANLANT C. ; STEVENIN J. ; BOURGEOUS C. F. (2010) Antagonistic factors control the unproductive splicing of SC35 terminal intron. Nucleic Acids Res 38 : 1353-1366
  • MAENNER S. ; BLAUD M. ; FOUILLEN L. ; SAVOYE A.. ; MARCHAND V. ; DUBOIS A. ; SANGLIER-CIANFERANI S. ; VAN DORSSELAER A. ; CLERC P. ; AVNER P. ; VISVIKIS A. ; BRANLANT C.(2010) 2-D structure of the A region of Xist RNA and its implication for PRC2 association. PLoS Biol 8 : e1000276
  • MOTORIN Y. ; HELM M. (2010) tRNA stabilization by modified nucleotides. Biochemistry 49 : 4934-4944
  • MOTORIN Y. ; LYKO F. ; HELM M. (2010) 5-methylcytosine in RNA : detection, enzymatic formation and biological functions. Nucleic Acids Res 38 : 1415-1430
  • TAZI J. ; BAKKOUR N. ; MARCHAND V. ; AYADI L. ; ABOUFIRASSI A. ; BRANLANT C. (2010) Alternative splicing : regulation of HIV-1 multiplication as a target for therapeutic action. FEBS J 277 : 867-876

2009

  • MULLER S. ; URBAN A. ; HECKER A. ; LECLERC F. ; BRANLANT C. ; MOTORIN Y. (2009) Deficiency of the tRNATyr:Psi 35-synthase aPus7 in Archaea of the Sulfolobales order might be rescued by the H/ACA sRNA-guided machinery. Nucleic Acids Res 37 : 1308-1322
  • SALIOU J. M. ; BOURGEOIS C. F. ; AYADI-BEN MENA L. ; ROPERS D. ; JACQUENET S. ; MARCHAND V. ; STEVENIN J. ; BRANLANT C. (2009) Role of RNA structure and protein factors in the control of HIV-1 splicing. Front Biosci 14 : 2714-2729
  • URBAN A. ; BEHM-ANSMANT I. ; BRANLANT C. ; MOTORIN Y. (2009) RNA sequence and two-dimensional structure features required for efficient substrate modification by the Saccharomyces cerevisiae RNA :Psi-synthase Pus7p. J Biol Chem 284 : 5845-5858

2008

  • BOULON S. ; MARMIER-GOURRIER N. ; PRADET-BALADE B. ; WURTH L. ; VERHEGGEN C. ; JADY B. E. ; ROTHE B. ; PESCIA C. ; ROBERT M. C. ; KISS T. ; BARDONI B. ; KROL A. ; BRANLANT C. ; ALLMANG C. ; BERTRAND É. ; CHARPENTIER B. (2008) The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery. J Cell Biol 180 : 579-595
  • MULLER S. ; LECLERC F. ; BEHM-ANSMANT I. ; FOURMANN J. B. ; CHARPENTIER B. ; BRANLANT C. (2008) Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAs. Nucleic Acids Res 36 : 2459-2475
  • PIAZZON N. ; RAGE F. ; SCHLOTTER F. ; MOINE H. ; BRANLANT C. ; MASSENET S. (2008) In vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation protein. J Biol Chem 283 : 5598-5610

2007

  • BAKKOUR N. ; LIN Y. L. ; MAIRE S. ; AYADI L. ; MAHUTEAU-BETZER F. ; NGUYEN C. H. ; METTLING C. ; PORTALES P. ; GRIERSON D. ; CHABOT B. ; JEANTEUR P. ; BRANLANT C. ; CORBEAU P. ; TAZI J. (2007) Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance. PLoS Pathog 3 : 1530-1539
  • BEHM-ANSMANT I. ; BRANLANT C. ; MOTORIN Y. (2007) The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Psi27/28-synthase. RNA 13 : 1641-1647
  • CHARPENTIER B. ; FOURMANN J. B. ; BRANLANT C. (2007) Reconstitution of archaeal H/ACA sRNPs and test of their activity. Meth Enzymol 425 : 389-405
  • CLERY A. ; BOURGUIGNON-IGEL V. ; ALLMANG C. ; KROL A. ; BRANLANT C. (2007) An improved definition of the RNA-binding specificity of SECIS-binding protein 2, an essential component of the selenocysteine incorporation machinery. Nucleic Acids Res 35 : 1868-1884
  • CLERY A. ; SENTY-SEGAULT V. ; LECLERC F. ; RAHE H. A. ; BRANLANT C. (2007) Analysis of sequence and structural features that identify the B/C motif of U3 small nucleolar RNA as the recognition site for the Snu13p-Rrp9p protein pair. Mol Cell Biol 27 : 1191-1206
  • MOTORIN Y. ; MULLER S. ; BEHM-ANSMANT I. ; BRANLANT C. (2007) Identification of modified residues in RNAs by reverse transcription-based methods. Meth Enzymol 425 : 21-53 –
  • MULLER S. ; CHARPENTIER B. ; BRANLANT C. ; LECLERC F. (2007) A dedicated computational approach for the identification of archaeal H/ACA sRNAs. Meth Enzymol 425 : 355-387
  • MULLER S. ; FOURMANN J. B. ; LOEGLER C. ; CHARPENTIER B. ; BRANLANT C. (2007) Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:Psi-synthase activities. Nucleic Acids Res 35 : 5610-5624

2006

  • BEHM-ANSMANT I. ; MASSENET S. ; IMMEL F. ; PATTON J. R. ; MOTORIN Y. ; BRANLANT C. (2006) A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs. RNA 12 : 1583-1593
  • HALLAY H. ; LOCKER N. ; AYADI L. ; ROPERS D. ; GUITTET E. ; BRANLANT C. (2006) Biochemical and NMR study on the competition between proteins SC35, SRp40, and heterogeneous nuclear ribonucleoprotein A1 at the HIV-1 Tat exon 2 splicing site. J Biol Chem 281 : 37159-37174
  • MANIVAL X. ; CHARRON C. ; FOURMANN J. B. ; GODARD F. ; CHARPENTIER B. ; BRANLANT C. (2006) Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity. Nucleic Acids Res 34 : 826-839

2005

  • BARDEY V. ; VALLET C. ; ROBAS N. ; CHARPENTIER B. ; THOUVENOT B. ; MOUGIN A. ; HAJNSDORF E. ; REGNIER P. ; SPRINGER M. ; BRANLANT C. (2005) Characterization of the molecular mechanisms involved in the differential production of erythrose-4-phosphate dehydrogenase, 3-phosphoglycerate kinase and class II fructose-1,6-bisphosphate aldolase in Escherichia coli. Mol Microbiol 57 : 1265-1287 
  • CHARPENTIER B. ; MULLER S. ; BRANLANT C. (2005) Reconstitution of archaeal H/ACA small ribonucleoprotein complexes active in pseudouridylation. Nucleic Acids Res 33 : 3133-3144