Responsables :




RNA-RNP Structure Fonction Maturation



  • Baldini L, Robert A, Charpentier B, Labialle S. Phylogenetic and molecular analyses identify SNORD116 targets involved in the Prader Willi syndrome. Mol Biol Evol. 2021 Dec 6:msab348. doi: 10.1093/molbev/msab348.PMID: 34893870
  • Xhaard C, Rouget R, Vodovar N, Le Floch E, Dandine-Roulland C, Wagner S, Bacq-Daian D, Thuillier Q, Boivin JM, Branlant C, Deleuze JF,  Behm-Ansmant I, Zannad F, Rossignol P, Girerd N. Impact of natriuretic peptide polymorphisms on diastolic and metabolic function in a populational cohort: insights from the STANISLAS cohort. ESC Heart Fail. 2021 Nov 3. doi: 10.1002/ehf2.13674
    PMID: 34734498
  • Marchand V, Bourguignon-Igel V, Helm M, Motorin Y. Analysis of pseudouridines and other RNA modifications using HydraPsiSeq protocol.Methods. 2021 Sep 1:S1046-2023(21)00206-1. doi: 10.1016/j.ymeth.2021.08.008. Online ahead of print.PMID: 34481083
  • Motorin Y, Quinternet M, Rhalloussi W, Marchand V. Constitutive and variable 2′-O-methylation (Nm) in human ribosomal RNA. RNA Biol. 2021 Sep 10:1-10. doi: 10.1080/15476286.2021.1974750. Online ahead of print.PMID: 34503375
  • Marchand V, Bourguignon-Igel V, Helm M, Motorin Y. Mapping of 7-methylguanosine (m7G), 3-methylcytidine (m3C), dihydrouridine (D) and 5-hydroxycytidine (ho5C) RNA modifications by AlkAniline-Seq. Methods Enzymol. 2021;658:25-47. doi: 10.1016/bs.mie.2021.06.001. Epub 2021 Jul 12.PMID: 34517949
  • Barthel H, Darne C, Gaté L, Visvikis A, Seidel C. Continuous Long-Term Exposure to Low Concentrations of MWCNTs Induces an Epithelial-Mesenchymal Transition in BEAS-2B Cells. Nanomaterials (Basel). 2021 Jul 1;11(7):1742. doi: 10.3390/nano11071742. PMID: 34361127
  • Alfeghaly C, Sanchez A, Rouget R, Thuillier Q, Igel-Bourguignon V, Marchand V, Branlant C, Motorin Y, Behm-Ansmant I, Maenner S. Implication of repeat insertion domains in the trans-activity of the long non-coding RNA ANRIL. Nucleic Acids Res. 2021 Apr 19 PMID: 33872355
  • Dermouche S, Chagot ME, Manival X, Quinternet M. Optimizing the First TPR Domain of the Human SPAG1 Protein Provides Insight into the HSP70 and HSP90 Binding Properties. Biochemistry. 2021 Mar 19. doi: 10.1021/acs.biochem.1c00052. PMID: 33739091.

  • Bragantini B, Charron C, Bourguet M, Paul A, Tiotiu D, Rothé B, Marty H, Terral G, Hessmann S, Decourty L, Chagot ME, Strub JM, Massenet S, Bertrand E, Quinternet M, Saveanu C, Cianférani S, Labialle S, Manival X, Charpentier B. The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106and controls its transcription dependent activity. Nat Commun. 2021 Mar doi: 10.1038/s41467-021-22077-4. PMID: 33767140
  • Relier S, Ripoll J, Guillorit H, Amalric A, Achour C, Boissière F, VialaretJ, Attina A, Debart F, Choquet A, Macari F, Marchand V, Motorin Y, Samalin E, Vasseur JJ, Pannequin J, Aguilo F, Lopez-Crapez E, Hirtz C, Rivals E, Bastide A, David A. FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell. Nat Commun. 2021 Mar19 doi: 10.1038/s41467-021-21758-4. PMID: 33741917
  • Azevedo-Favory J, Gaspin C, Ayadi L, Montacié C, Marchand V, Jobet E, RompaisM, Carapito C, Motorin Y, Sáez-Vásquez J. Mapping rRNA 2′-O-methylations and identification of C/D snoRNAs in Arabidopsis thaliana plants. RNA Biol. 2021 Feb doi: 10.1080/15476286.2020.1869892.  PMID:33596769.
  • Heiss M, Hagelskamp F, Marchand V, Motorin Y, Kellner S. Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo. Nat Commun. 2021 Jan  doi: 10.1038/s41467-020-20576-4. PMID: 33452242
  • Werner S, Galliot A, Pichot F, Kemmer T, Marchand V, Sednev MV, Lence T, Roignant JY, König J, Höbartner C, Motorin Y, Hildebrandt A, Helm M. NOseq:amplicon sequencing evaluation method for RNA m6A sites after chemical deamination. Nucleic Acids Res. 2021 Feb  doi:10.1093/nar/gkaa1173. PMID: 33313868; PMCID: PMC7913672.
  • Pichot F, Marchand V, Helm M, Motorin Y. Non-Redundant tRNA Reference Sequences for Deep Sequencing Analysis of tRNA Abundance and Epitranscriptomic RNA Modifications. Genes (Basel). 2021 Jan doi:10.3390/genes12010081. PMID: 33435213
  • Abel Y, Paiva ACF, Bizarro J, Chagot ME, Santo PE, Robert MC, Quinternet M, Vandermoere F, Sousa PMF, Fort P, Charpentier B, Manival X, Bandeiras TM, Bertrand E, Verheggen C. NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis. Nucleic Acids Res. 2021 Jan doi: 10.1093/nar/gkaa1226. PMID: 33367824

Chapîtres de methodologie

  • Baldini L, Labialle S. Using Native RIP, UV-CLIP or fCLIP to Address Protein-RNA Interactions In Vivo. Methods Mol Biol. 2021;2300:89-98. doi: 10.1007/978-1-0716-1386-3_9.PMID: 33792874
  • Sanchez A, Maenner S. Purification of RiboNucleoProtein Particles by MS2-MBP Affinity Chromatography. Methods Mol Biol. 2021;2300:99-106. doi: 10.1007/978-1-0716-1386-3_10. PMID: 33792875
  • Marchand V, Ayadi L, Bourguignon-Igel V, Helm M, Motorin Y. AlkAniline-Seq: A Highly Sensitive and Specific Method for Simultaneous Mapping of 7-Methyl-guanosine (m7G) and 3-Methyl-cytosine (m3C) in RNAs by High-Throughput Sequencing. Methods Mol Biol. 2021;2298:77-95. doi: 10.1007/978-1-0716-1374-0_5.PMID: 34085239
  • Abel Y, Rederstorff M. Gene Reporter Assays to Study miRNA Function. Methods Mol Biol. 2021;2300:119-131. doi: 10.1007/978-1-0716-1386-3_12. PMID: 33792877.
  • Abel Y, Rederstorff M. Stem-Loop qRT-PCR-Based Quantification of miRNAs. Methods Mol Biol. 2021;2300:59-64. doi: 10.1007/978-1-0716-1386-3_6. PMID:33792871.
  • Bourguignon-Igel V, Abel Y, Rederstorff M. RNA Precipitation. Methods Mol Biol. 2021;2300:11-16. doi: 10.1007/978-1-0716-1386-3_2. PMID: 33792867.
  • Virciglio C, Abel Y, Rederstorff M. Regulatory Non-Coding RNAs: An Overview. Methods Mol Biol. 2021;2300:3-9. doi: 10.1007/978-1-0716-1386-3_1. PMID:33792866.
  • Thuillier Q, Behm-Ansmant I. Microarray Analysis of Whole-Transcriptome RNAs Including Non-Coding RNAs. Methods Mol Biol. 2021;2300:143-164. doi:10.1007/978-1-0716-1386-3_14. PMID: 33792879.
  • Alfeghaly C, Behm-Ansmant I, Maenner S. Study of Genome-Wide Occupancy of Long Non-Coding RNAs Using Chromatin Isolation by RNA Purification (ChIRP). Methods Mol Biol. 2021;2300:107-117. doi: 10.1007/978-1-0716-1386-3_11. PMID:33792876.
  • Vautrot V, Heckler G, Aigueperse C, Behm-Ansmant I. Fluorescence In Situ Hybridization of Small Non-Coding RNAs. Methods Mol Biol. 2021;2300:73-85. doi:10.1007/978-1-0716-1386-3_8. PMID: 33792873.
  • Alfeghaly C, Aigueperse C, Maenner S, Behm-Ansmant I. Non-Coding RNA Silencing in Mammalian Cells by Antisense LNA GapmeRs Transfection. Methods Mol Biol. 2021;2300:31-37. doi: 10.1007/978-1-0716-1386-3_4. PMID: 33792869.
  • Marchand V, Galvanin A, Motorin Y. Isolation, Extraction and Deep-Sequencing Analysis of Extracellular RNAs (exRNAs) from Human Plasma. Methods Mol Biol.2021;2300:165-182. doi: 10.1007/978-1-0716-1386-3_15. PMID: 33792880.
  • Marchand V, Ayadi L, Bourguignon-Igel V, Motorin Y. Quantitative and Qualitative Assessment of Small RNA Preparations. Methods Mol Biol.2021;2300:17-29. doi: 10.1007/978-1-0716-1386-3_3. PMID: 33792868
  • Chagot ME, Quinternet M, Manival X, Lebars I. Application of NMR Spectroscopy to Determine the 3D Structure of Small Non-Coding RNAs. Methods Mol Biol. 2021;2300:251-266. doi: 10.1007/978-1-0716-1386-3_19. PMID: 33792884


  • Baldini L, Charpentier B, Labialle S. Emerging Data on the Diversity of Molecular Mechanisms Involving C/D snoRNAs.  Noncoding RNA. 2021 May 6;7(2):30. doi: 10.3390/ncrna7020030. PMID: 34066559
  • Marchand V, Motorin Y. Detection and functions of viral RNA modifications: perspectives in biology and medicine. Virologie (Montrouge). 2021 Apr 1;25(2):5-20. doi: 10.1684/vir.2021.0884.PMID: 33973850 
  • Motorin Y, Marchand V. Analysis of RNA Modifications by Second- and Third-Generation Deep Sequencing: 2020 Update. Genes (Basel). 2021 Feb doi: 10.3390/genes12020278. PMID: 33669207.
  • Yoluç Y, Ammann G, Barraud P, Jora M, Limbach PA, Motorin Y, Marchand V, Tisné C, Borland K, Kellner S. Instrumental analysis of RNA modifications. CritRev Biochem Mol Biol. 2021 Apr doi:10.1080/10409238.2021.1887807. PMID: 33618598.



  •  Marcel V, Kielbassa J, Marchand V, Natchiar KS, Paraqindes H, Nguyen Van Long F, Ayadi L, Bourguignon-Igel V, Lo Monaco P, Monchiet D, Scott V, Tonon L, Bray SE, Diot A, Jordan LB, Thompson AM, Bourdon J-C, Dubois T,  André F,  Catez F, Puisieux A, Motorin Y, Klaholz BP, Viari A, Diaz J-J. (2020). Ribosomal RNA 2′O-methylation as a novel layer of inter-tumour heterogeneity in breast cancer. NAR Cancer, 2(4): pp.zcaa036.

  • Marchand V, Pichot F, Neybecker P, Ayadi LBourguignon-Igel V, Wacheul L, Lafontaine DLJ, Pinzano A, Helm M, Motorin Y. HydraPsiSeq : a method for systematic and quantitative mapping of pseudouridines in RNA. Nucleic Acids Res. 2020 Sep 25:gkaa769. doi : 10.1093/nar/gkaa769. PMID : 32976574
  • ABEL, Y.; PAIVA, A.C.F.; BIZARRO, J.; CHAGOT, M.-E.; SANTO, P.E.; ROBERT, M.-C.; QUINTERNET, M.; VANDERMOERE, F.; SOUSA, P.M.F.; FORT, P.; CHARPENTIER, B.; MANIVAL, X.; BANDEIRAS, T.M.; BERTRAND, E. and VERHEGGEN, C. (2020). NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis. Nucleic Acids Res. 49(2):1094-1113. PMID: 33367824
  •  GALVANIN, A.; VOGT, L.M.; GROBER, A.; FREUND, I.; AYADI, L.; BOURGUIGNON-IGEL, V.; BESSLER, L.; JACOB, D.; EIGENBROD, T., MARCHAND, V.; DALPKE, A.; HELM, M. and MOTORIN, Y. (2020). Bacterial tRNA 2’-O-methylation is dynamically regulated under stress conditions and modulates innate immune response. Nucleic Acids Res. 2020 Dec 4:gkaa1123. doi : 10.1093/nar/gkaa1123. PMID: 33275131
  • Kristen M, Plehn J, Marchand V, Friedland K, Motorin Y, Helm M, Werner S. Manganese Ions Individually Alter the Reverse Transcription Signature of Modified Ribonucleosides. Genes (Basel). 2020 Aug 18 ;11(8):E950. doi : 10.3390/genes11080950. PMID : 32824672 
  • Heckler G, Aigueperse C, Hettal L, Thuillier Q, de Chaumont F, Dallongeville S, Behm-Ansmant I. Substructure Analyzer : A User-Friendly Workflow for Rapid Exploration and Accurate Analysis of Cellular Bodies in Fluorescence Microscopy Images.  J Vis Exp. 2020 Jul 15 ;(161). doi : 10.3791/60990. PMID : 32744525
  • de Crécy-Lagard V, Ross RL, Jaroch M,Marchand V, Eisenhart C, Brégeon D, Motorin Y, Limbach PA. Survey and Validation of tRNA Modifications and Their Corresponding Genes in Bacillus subtilis sp Subtilis Strain 168. Biomolecules. 2020 Jun 30 ;10(7):E977. doi : 10.3390/biom10070977. PMID : 32629984
  • Trzaska C, Amand S, Bailly C, Leroy C, Marchand V, Duvernois-Berthet E, Saliou JM, Benhabiles H, Werkmeister E, Chassat T, Guilbert R, Hannebique D, Mouray A, Copin MC, Moreau PA, Adriaenssens E, Kulozik A, Westhof E, Tulasne D, Motorin Y, Rebuffat S, Lejeune F. 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations. Nat Commun. 2020 Mar 20 ;11(1):1509. doi : 10.1038/s41467-020-15140-z. PMID : 32198346 
  • Pichot F, Marchand V, Ayadi L, Bourguignon-Igel V, Helm M, Motorin Y. Holistic Optimization of Bioinformatic Analysis Pipeline for Detection and Quantification of 2’-O-Methylations in RNA by RiboMethSeq. Front Genet2020 Feb 13 ;11:38. doi : 10.3389/fgene.2020.00038. PMID : 32117451
  • Werner S, Schmidt L, Marchand V, Kemmer T, Falschlunger C, Sednev MV, Bec G, Ennifar E, Höbartner C, Micura R, Motorin Y, Hildebrandt A, Helm M. Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes. Nucleic Acids Res. 2020 Feb 25. pii : gkaa113. doi : 10.1093/nar/gkaa113. PMID : 32095818
  • Chagot ME, Quinternet M, Jacquemin C, Manival X, Gardiennet C. Box C/D snoRNPs : solid-state NMR fingerprint of an early-stage 50 kDa assembly intermediate. Biomol NMR Assign. 2020 Feb 6. doi : 10.1007/s12104-020-09933-y. PMID : 32030621
  • Clerget G, Bourguignon-Igel V, Marmier-Gourrier N, Rolland N, Wacheul L, Manival X, Charron C, Kufel J, Méreau A, Senty-Ségault V, Tollervey D, Lafontaine DLJ, Branlant C, Rederstorff M. Synergistic defects in pre-rRNA processing from mutations in the U3-specific protein Rrp9 and U3 snoRNA. Nucleic Acids Res. 2020 Apr 17 ;48(7):3848-3868. doi : 10.1093/nar/gkaa066. PMID : 31996908
  • Angelova MT, Dimitrova DG, Da Silva B, Marchand V, Jacquier C, Achour C, Brazane M, Goyenvalle C, Bourguignon-Igel V, Shehzada S, Khouider S, Lence T, Guerineau V, Roignant JY, Antoniewski C, Teysset L, Bregeon D, Motorin Y, Schaefer MR, Carré C. tRNA 2’-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in DrosophilaNucleic Acids Res. 2020 Jan 16. pii : gkaa002. doi : 10.1093/nar/gkaa002. PMID : 31943105
Articles cliniques
  • HETTAL, L., STEFANI, A., SALLERON, J., COURRECH, F., BEHM-ANSMANT, I., CONSTANS, JM., GAUCHOTTE, G. and VOGIN, G. (2020). Radiomics Method for the Differential Diagnosis of Radionecrosis Versus Progression after Fractionated Stereotactic Body Radiotherapy for Brain Oligometastasis. Radiat Res. 193(5):471-480. PMID: 32160109

  • YAKAVETS I, FRANCOIS A, BENOIT A, MERLIN JL, BEZDETNAYA L, VOGIN G (2020). Advanced co-culture 3D breast cancer model for investigation of fibrosis induced by external stimuli: optimization study. Sci Rep. 2020 Dec 4;10(1):21273. doi: 10.1038/s41598-020-78087-7.PMID: 33277538
  • OBARA T, BLONSKI M, BRZENCZEK C, MÉZIÈRES S, GAUDEAU Y, POUGET C, … VOGIN G & al (2020). Adult Diffuse Low-Grade Gliomas: 35-Year Experience at the Nancy France Neurooncology Unit. Front Oncol. 2020 Oct 28;10:574679. doi: 10.3389/fonc.2020.574679. eCollection 2020. PMID: 33194684
  • VOGIN, G ; FAUVEL, M ; HOSSU, G ; BEAUMONT, M ; MICARD, E ; FELTGEN, K & al (2020), Assessing the neuroanatomy knowledge and spatial ability of radiotherapy technologist undergraduates using an interactive volumetric simulation tool-the RadioLOG project., Eur Radiol, 2020, Oct 10. doi: 10.1007/s00330-020-07351-1; PMID: 33037914


  • Rederstorff M. [Decoupling of pre-ribosomal RNA early cleavages by a point mutation in the U3 snoRNA-specific protein Rrp9] Med Sci (Paris). 2020 Apr ;36(4):329-331. Article in French
    PMID : 32356707 

Chapître de methodologie

  • Vautrot V, Behm-Ansmant I. Enhanced Probe-Based RT-qPCR Quantification of MicroRNAs Using Poly(A) Tailing and 5’ Adaptor Ligation. Methods Mol Biol. 2020 ;2065:39-54.  PMID : 31578686


  • ACL-28 Khoury G, Mackenzie C, Ayadi L, Lewin SR, Branlant C, Purcell DFJ. Tat IRES modulator of tat mRNA (TIM-TAM) : a conserved RNA structure that controls Tat expression and acts as a switch for HIV productive and latent infection. Nucleic Acids Res. 2019 Dec 25. pii : gkz1181. doi : 10.1093/nar/gkz1181. 2019 Q1, IF 11.501
    PMID : 31875221 
  • REV-10 Helm M, Lyko F, Motorin Y. Limited antibody specificity compromises epitranscriptomic analyses. Nat Commun. 2019 Dec 11 ;10(1):5669. doi : 10.1038/s41467-019-13684-3. Comment. 2019 Q1, IF 12.121
    PMID : 31827101 
  • ACL-27 Schmidt L, Werner S, Kemmer T, Niebler S, Kristen M, Ayadi L, Johe P, Marchand V, Schirmeister T, Motorin Y, Hildebrandt A, Schmidt B, Helm M. Graphical Workflow System for Modification Calling by Machine Learning of Reverse Transcription Signatures. Front Genet. 2019 Sep 25 ;10:876. doi : 10.3389/fgene.2019.00876. 2019 Q2, IF 3.258
    PMID : 31608115 
  • ACL-25 Chagot ME, Dos Santos Morais R, Dermouche S, Lefebvre D, Manival X, Chipot C, Dehez F, Quinternet M. Binding properties of the quaternary assembly protein SPAG1. Biochem J. 2019 Jun 14 ;476(11):1679-1694. doi : 10.1042/BCJ20190198. 2019 Q2, IF 4.097
    PMID : 31118266
  • REV-8 Motorin Y, Massenet S. RNA structure, maturation, interactions and functions. Editorial introduction forthe Special issue dedicated to 2019 SIFRARN meeting in Nancy. Biochimie. 2019 Jul 17. pii : S0300-9084(19)30204-4. doi:10.1016/j.biochi.2019.07.013. Review. 2019 Q2, IF 3.413
    PMID : 31325478
  • REV-6 Abel Y, Rederstorff M. SnoRNAs and the emerging class of sdRNAs : Multifaceted players in oncogenesis. Biochimie. 2019 May 9. pii : S0300-9084(19)30145-2. doi : 10.1016/j.biochi.2019.05.006. Review. 22019 Q2, IF 3.413
    PMID : 31078583
  • ACL-21 Galvanin A, Dostert G, Ayadi L, Marchand V, Velot É, Motorin Y. Diversity and heterogeneity of extracellular RNA in human plasma. Biochimie. 2019 May 17. pii : S0300-9084(19)30150-6. doi : 10.1016/j.biochi.2019.05.011. 2019 Q2, IF 3.413
    PMID : 31108123
  • ACL-20 Freund I, Buhl DK, Boutin S, Kotter A, Pichot F, Marchand V, Vierbuchen T, Heine H, Motorin Y, Helm M, Dalpke AH, Eigenbrod T. 2’-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms. RNA. 2019 Apr 24. pii : rna.070243.118. doi : 10.1261/rna.070243.118. 2019 Q2, IF 4.320
    PMID : 31019095
  • REV-7 Massenet S. In vivo assembly of eukaryotic signal recognition particle : A still enigmatic process involving the SMN complex. Biochimie. 2019 Apr 9. pii : S0300-9084(19)30109-9. doi : 10.1016/j.biochi.2019.04.007. Review. 2019 Q2, IF 3.413
    PMID : 30978374
  • ACL-19 Chagot ME, Quinternet M, Rothé B, Charpentier B, Coutant J, Manival X, Lebars I. The yeast C/D box snoRNA U14 adopts a « weak » K-turn like conformation recognized by the Snu13 core protein in solution. Biochimie. 2019 Mar 23. pii : S0300-9084(19)30083-5. doi : 10.1016/j.biochi.2019. 03.014.2019 Q2, IF 3.413
    PMID : 30914254
  • ACL-23 Paul A, Tiotiu D, Bragantini B, Marty H, Charpentier B, Massenet S, Labialle S. Bcd1p controls RNA loading of the core protein Nop58 during C/D box snoRNP biogenesis. RNA. 2019 Apr ;25(4):496-506. doi : 10.1261/rna.067967.118. 2019 Q2, IF 4.320
    PMID : 30700579
  • ACL-22 Jacob D, Thüring K, Galliot A, Marchand V, Galvanin A, Ciftci A, Scharmann K, Stock M, Roignant JY, Leidel SA, Motorin Y, Schaffrath R, Klassen R, Helm M. Absolute quantification of noncoding RNA by microscale thermophoresis.Angew Chem Int Ed Engl. 2019 Mar 20. doi : 10.1002/anie.201814377. 2019 Q1, IF 12.959
    PMID : 30892798.
  • ACL-26 Wei J, Kishton RJ, Angel M, Conn CS, Dalla-Venezia N, Marcel V, Vincent A, Catez F, Ferré S, Ayadi L, Marchand V, Dersh D, Gibbs JS, Ivanov IP, Fridlyand N, Couté Y, Diaz JJ, Qian SB, Staudt LM, Restifo NP, Yewdell JW. Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance. Mol Cell. 2019 Jan 24. pii : S1097-2765(18)31096-7. doi : 10.1016/j.molcel.2018.12.020. 2019 Q1, IF 15.584
    PMID : 30712990.
  • REV-9 Motorin Y, Helm M. Methods for RNA Modification Mapping Using Deep Sequencing : Established and New Emerging Technologies. Genes (Basel). 2019 Jan 9 ;10(1). pii : E35. doi : 10.3390/genes10010035. Review. 2019 Q2, IF 3.759
    PMID : 30634534.
  • ACL-24 Ringeard M, Marchand V, Decroly E, Motorin Y, Bennasser Y. FTSJ3 is an RNA 2’-O-methyltransferase recruited by HIV to avoid innate immune sensing. Nature. 2019 Jan 9. doi : 10.1038/s41586-018-0841-4. 2019 Q1, IF 42.778
  • CHAP-3 Galvanin A, Ayadi L, Helm M, Motorin Y, Marchand V. Mapping and Quantification of tRNA 2’-O-Methylation by RiboMethSeq. Methods Mol Biol. 2019 ;1870:273-295. doi : 10.1007/978-1-4939-8808-2_21.
    PMID : 30539563


  • REV-5 Ayadi L, Galvanin A, Pichot F, Marchand V, Motorin Y. RNA ribose methylation (2’-O-methylation) : Occurrence, biosynthesis and biological functions. Biochim Biophys Acta Gene Regul Mech. 2018 Dec 17. pii : S1874-9399(18)30080-4. doi : 10.1016/j.bbagrm.2018.11.009. Review. 2018 Q1, IF 4.599
    PMID : 30572123
  • REV-4 Motorin Y, Marchand V. Detection and Analysis of RNA Ribose 2’-O-Methylations : Challenges and Solutions. Genes (Basel). 2018 Dec 18 ;9(12). pii : E642. doi : 10.3390/genes9120642. Review. 2018 Q2, IF 3.331
    PMID : 30567409
  • ACL-16 Marchand V, Ayadi L, Ernst FGM, Hertler J, Bourguignon-Igel V, Galvanin A, Kotter A, Helm M, Lafontaine DLJ, Motorin Y. AlkAniline-Seq : profiling of m7G and m3C RNA modifications at single nucleotide resolution. Angew Chem Int Ed Engl. 2018 Oct 29. doi : 10.1002/anie.201810946. 2018 Q1, IF 12.257
    PMID : 30370969
  • ACL-12 Fujikane R, Behm-Ansmant I, Tillault AS, Loegler C, Igel-Bourguignon V, Marguet E, Forterre P, Branlant C, Motorin Y, Charpentier B. Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA :Ψ-synthase activities of the archaeal Cbf5 protein.Sci Rep. 2018 Sep 14 ;8(1):13815. doi : 10.1038/s41598-018-32164-0. 2018 Q1, IF 4.011
  • ACL-15 Keller P, Freund I, Marchand V, Bec G, Huang R, Motorin Y, Eigenbrod T, Dalpke A, Helm M. Double methylation of tRNA-U54 to 2’-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7. Nucleic Acids Res. 2018 Aug 8. doi : 10.1093/nar/gky644. 2018 Q1, IF 11.147
  • ACL-14 Henri J, Chagot ME, Bourguet M, Abel Y, Terral G, Maurizy C, Aigueperse C, Georgescauld F, Vandermoere F, Saint-Fort R, Behm-Ansmant I, Charpentier B, Pradet-Balade B, Verheggen C, Bertrand E, Meyer P, Cianférani S, Manival X, Quinternet M. Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. Structure. 2018 Jul 18. pii : S0969-2126(18)30208-9. doi : 10.1016/j.str.2018.06.002. 2018 Q1, IF 4.576
  • REV-3 Jantsch MF, Quattrone A, O’Connell M, Helm M, Frye M, Macias-Gonzales M, Ohman M, Ameres S, Willems L, Fuks F, Oulas A, Vanacova S, Nielsen H, Bousquet-Antonelli C, Motorin Y, Roignant JY, Balatsos N, Dinnyes A, Baranov P, Kelly V, Lamm A, Rechavi G, Pelizzola M, Liepins J, Holodnuka Kholodnyuk I, Zammit V, Ayers D, Drablos F, Dahl JA, Bujnicki J, Jeronimo C, Almeida R, Neagu M, Costache M, Bankovic J, Banovic B, Kyselovic J, Valor LM, Selbert S, Pir P, Demircan T, Cowling V, Schäfer M, Rossmanith W, Lafontaine D, David A, Carre C, Lyko F, Schaffrath R, Schwartz S, Verdel A, Klungland A, Purta E, Timotijevic G, Cardona F, Davalos A, Ballana E, O Carroll D, Ule J, Fray R. Positioning Europe for the EPITRANSCRIPTOMICS challenge. RNA Biol. 2018 May 9:1-3. doi : 10.1080/15476286.2018.1460996. Review. 2018 Q1, IF 5.477
  • ACL-17 Maurizy C, Quinternet M, Abel Y, Verheggen C, Santo PE, Bourguet M, C F Paiva A, Bragantini B, Chagot ME, Robert MC, Abeza C, Fabre P, Fort P, Vandermoere F, M F Sousa P, Rain JC, Charpentier B, Cianférani S, Bandeiras TM, Pradet-Balade B, Manival X, Bertrand E. The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones. Nat Commun. 2018 May 29 ;9(1):2093. doi : 10.1038/s41467-018-04431-1. 2018 Q1, IF 11.878
  • ACL-11 Dal Magro C, Keller P, Kotter A, Werner S, Duarte V, Marchand V, Ignarski M, Freiwald A, Müller RU, Dieterich C, Motorin Y, Butter F, Atta M, Helm M. A vastly increased chemical variety of RNA modifications that includes a thioacetal structure. Angew Chem Int Ed Engl. 2018 Apr 6. doi : 10.1002/anie.201713188. 2018 Q1, IF 12.257
    PMID : 29624844
  • ACL-10 Bragantini B, Rouillon C, Charpentier B, Manival X, Quinternet M. NMR assignment and solution structure of the external DII domain of the yeast Rvb2 protein. Biomol NMR Assign. 2018 Mar 22. doi : 10.1007/s12104-018-9816-5. 2018 Q4, IF 0.576
    PMID : 29569106
  • ACL-18 Weldon C, Dacanay JG, Gokhale V, Boddupally PVL, Behm-Ansmant I, Burley GA, Branlant C, Hurley LH, Dominguez C, Eperon IC. Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X. Nucleic Acids Res. 2018 Jan 25 ;46(2):886-896. doi : 10.1093/nar/gkx1122. 2018 Q1, IF 11.147
    PMID : 29156002
  • CHAP- 2 Ayadi L, Motorin Y, Marchand V. Quantification of 2’-O-Me Residues in RNA Using Next-Generation Sequencing (Illumina RiboMethSeq ProtoACL-14 col). Methods Mol Biol. 2018 ;1649:29-48. doi : 10.1007/978-1-4939-7213-5_2.
  • ACL-13 Guéant JL, Chéry C, Oussalah A, Nadaf J, Coelho D, Josse T, Flayac J, Robert A, Koscinski I, Gastin I, Filhine-Tresarrieu P, Pupavac M, Brebner A, Watkins D, Pastinen T, Montpetit A, Hariri F, Tregouët D, Raby BA, Chung WK, Morange PE, Froese DS, Baumgartner MR, Benoist JF, Ficicioglu C, Marchand V, Motorin Y, Bonnemains C, Feillet F, Majewski J, Rosenblatt DS. A PRDX1 mutant allele causes a MMACHC secondary epimutation in cblC patients. Nat Commun. 2018 Jan 4 ;9(1):67. doi : 10.1038/s41467-017-02306-5. Erratum in : Nat Commun. 2018 Feb 2 ;9(1):554. 2018 Q1, IF 11.878
    PMID : 29302025
  • ACL-9 Aschenbrenner J, Werner S, Marchand V, Adam M, Motorin Y, Helm M, Marx A. Engineering of a DNA Polymerase for Direct m6A Sequencing. Angew Chem Int Ed Engl. 2018 Jan 8 ;57(2):417-421. doi : 10.1002/anie.201710209. 2018 Q1, IF 12.257
    PMID : 29115744